The human cerebellum is not just involved in motor control - indeed, most of the cerebellum is specifically activated for cognitive functions, such as working memory, cognitive control, action observation, language, and social cognition. In our research, we use fMRI to understand the functional heterogeneity of the human cerebellum. Using a rich, multi-domain task battery we recently generated a new functional atlas (King et al., 2018), which will be integrated in the SUIT toolbox and can serve as a general resource for functional localisation. These data show the presence of real functional boundaries in the cerebellum. Currently, we are using the data set to test different models of interactions between neocortex and cerebellum. More precise cerebellar maps will be essential to understand the involvement of the cerebellum in neuropsychiatric disorders, such as Schizophrenia (Moberget et al., 2018), Autism and Dyslexia.
This research is supported by a grant from the CIHR (PJT 159520).
- King, M., Hernandez-Castillo, C.R., Poldrack, R. Ivry, R., Diedrichsen, J. (2018). A multi-domain task battery reveals functional boundaries in the human cerebellum. BioRxiv.
- Moberget, T., Doan, N. T., Alnaes, D., Kaufmann, T., Cordova-Palomera, A., Lagerberg, T. V., Diedrichsen, J.,...,Westlye, L. T. (2017). Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls. Mol Psychiatry, 23(6), 1512-1520.
- King, M., Hernandez-Castillo, C., & Diedrichsen, J. (2017). Towards a multi-function mapping of the cerebellar cortex. Brain, 140(3), 522-524.